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A and B, plasma ACTH (A) and corticosterone (CORT) (B) concentrations under resting conditions (basal) and following 30 min of restraint stress (restraint) in wild-type (WT, open bar) and mice genetically deficient for the gene (Kcnn4) encoding SK4 channels (Kcnn4−/−, filed bar). Data are means ± SEM, n = 7/group. **P < 0.01, ANOVA with post hoc Dunnett's test compared to WT.
