Table 3.
Thyroid cancer risk associated with different genotype combinations (diplotypes) at rs965513 and rs1867277
| rs965513 | rs1867277 | Frequency (%) | OR (95% CI) | p Value | |
| Cases | Controls | ||||
| GG | GG | 123 (0.162) | 1917 (0.315) | Reference | |
| AG | 60 (0.079) | 744 (0.122) | 1.257 (0.897 to 1.747) | 0.174 | |
| AA | 7 (0.009) | 73 (0.012) | 1.494 (0.568 to 3.333) | 0.336 | |
| AG | GG | 33 (0.043) | 355 (0.058) | 1.449 (0.939 to 2.183) | 0.071 |
| AG | 300 (0.394) | 1960 (0.322) | 2.385 (1.908 to 2.995) | 6.62×10−16 | |
| AA | 63 (0.083) | 394 (0.065) | 2.491 (1.774 to 3.473) | 1.10×10−7 | |
| AA | GG | 4 (0.005) | 17 (0.003) | 3.663 (0.883 to 11.465) | 0.036 |
| AG | 42 (0.055) | 174 (0.029) | 3.759 (2.497 to 5.580) | 4.44×10−10 | |
| AA | 129 (0.170) | 451 (0.074) | 4.455 (3.379 to 5.876) | 8.50×10−27 | |
The risk alleles are rs965513A and rs1867277A.