Fig. (5) .
RSV F specific antibody response and cellular response in rhesus macques vaccinated with measles vectors. Measles seronegative and sero-positive rhesus macaques were immunized with 105 PFU of sF3 or gp350 on day 0 and 28. (A) RSV F titers were measured on day 28 (post dose 1) and 42 (post dose 2) using ELISA. (B) PBMCs were isolated from whole blood on day 56. The numbers of IFN-γ spot forming cells were quantified with an ELISpot assay when PBMCs were stimulated with measles viral antigens, RSV F or EBV gp350 antigens in vitro. Spots were counted with an automated counting device and are expressed as numbers of spots per 106 cells ± SEM. ND = not determined.