Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Effects of therapeutic hypothermia on pharmacokinetic and pharmacodynamic parameters. Upon traumatic brain injury, stroke, and other brain insults, patients may receive pharmacotherapy as well as hypothermic treatment, which may influence the kinetic as well as dynamic parameters of pharmacotherapy. Patients should be carefully monitored to avoid drug toxicity and treatment failure. ADME; absorption, distribution, metabolism, and elimination.
