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Small molecule/kinase interaction maps for BRD7446 and BRD8899. The kinase profiling (16) was done at 5 μM for BRD7446 and 1 μM for BRD8899, resulting in equal inhibition of STK33 in a biochemical assay. Kinases found to bind are marked with red circles; larger circles indicate higher affinity binding. STK33 is indicated by the red arrow.
