Table 1.

Urine and serum chemistry profile in 12-mo-old WT and LXRβ^−/− mice

Chemistry profile	WT	LXRβ−/−
Urine
pH	7.2 ± 0.2	6.3 ± 0.1**
Glucose (mg/dL)	40.1 ± 4.2	23.9 ± 2.0*
Total Protein (mg/dL)	317 ± 36	55 ± 8**
Creatinine (mg/dL)	42.0 ± 3.5	18.7 ± 1.5**
Urea Nitrogen (mg/dL)	3085 ± 285	1535 ± 108**
Sodium (mmol/L)	114 ± 12	51 ± 4**
Potassium (mmol/L)	204 ± 19	122 ± 9**
Calcium (mg/dL)	14 ± 1	8 ± 1**
Magnesium (mg/dL)	55 ± 5	33 ± 2**
Phosphorus (mg/dL)	135 ± 9	86 ± 8**
Serum
Creatinine (mg/dL)	0.38 ± 0.06	0.37 ± 0.03

Data are presented as mean ± SEM; *P < 0.05; **P < 0.001 versus WT. n = 10 per group for the urine chemistry profile, and n = 5 per group for the serum creatinine.