Table 1.
Spontaneous models of B-cell lymphoma. B-NHL: non-Hodgkin B-cell lymphoma; CLL: chronic lymphocytic leukemia; DLBCL: diffuse large B-cell lymphoma; DTG: double transgenic mice; n.d.: not determined.
| Name | Lymphoma subtype/orgin | Strain (haplotype) | Major reference |
|---|---|---|---|
| B10 H-2a H-4bp/Wts | CLL | C57Bl/10 (H-2b) | [2] |
| SL/KH | Pre-B lymphoma | SL/KH (H-211) | [3] |
| Eμ-N-myc | Indolent B-NHL | C57Bl/6 x DBA/2 (H-2b/d) | [4] |
| NFS.V+ | Marginal zone lymphoma | NFS.V+ (H-2sq4) | [5] |
| NMRI/RFB-MuLV | n.d. | NMRI (H-2q) | [6] |
| B6-l-MYC | Burkitt-like lymphoma | C57Bl/6 (H-2b) | [7] |
| VavP-Bcl2 | Follicular lymphoma | C57Bl/6 (H-2b) | [8] |
| Lig4/p53 KO | Pro/Pre-B lymphoma | C57Bl/6 × sv129 | [9] |
| Eμ-BRD2 | DLBCL | FVB (H-2q) | [10] |
| Bcl6 Knock in | Germinal center, DLBCL | C57Bl/6 × sv129 | [11] |
| Bcl6/Myc transgenic | Post germinal center, DLBCL | C57Bl/6 × sv129 | [11] |
| IL-14aTGxc-Myc TG (DTG) | Blastoid variant of mantle-cell lymphoma | C57Bl/6 (H-2b) | [12] |
| Myc/BCRHEL/HEL | Burkitt-like lymphoma | C57Bl/6 (H-2b) | [13] |
| Eμ-myc | From follicular to DLBCL (time dependant) | C57Bl/6 × sv129 | [14] |
| RzCD19Cre | NHL, hepatitis C induced | 129/Sv (H-2bc); BALB/c (H-2d); C57Bl/6 (H-2b) | [15] |
| UVB induced | Mature B-cell lymphoma | C57Bl/6 p53+/− (H-2b) | [16] |