Table 5.
Comparison of the clinical evaluation
| Pleural fluid | Plasma | ||||
|---|---|---|---|---|---|
| Sequencing | ADx-ARMS | Sequencing | ADx-ARMS | ||
| Mutation positive |
Number (%) | 16(50%) | 22(68.8%) | 0 | 5(27.8%) |
| PR | 13 | 16 | 0 | 4 | |
| SD | 2 | 5 | 0 | 0 | |
| PD | 1 | 1 | 0 | 1 | |
| ORR | 81.3%a | 72.7%c | NA | 80%e | |
| Mutation negative | Number (%) | 16(50%) | 10(31.2%) | 18(100%) | 13(72.2%) |
| PR | 9 | 6 | 10 | 6 | |
| SD | 4 | 1 | 1 | 1 | |
| PD | 3 | 3 | 7 | 6 | |
| ORR | 56.3%b | 60%d | 55.6% | 46.2%f | |
PR = Partial Response; SD = Stable Disease; PD = Progressive Disease; ORR = Objective response rate
Between a and b, P = 0.2524; Between c and d, P = 0.6828; Between e and f, P = 0.3137; Between a and c, P = 0.706