Figure 2.

Enrichment of chromatin modifications and RNA Pol II at cis-NAT promoters. Cis-NAT promoters identified in the NHEK cell type were divided into four bins based on their activity (from lowest to highest activity), and the normalized average numbers of ChIP-seq reads from each histone modification ±5 kb of the cis-NAT TSS were calculated for each bin. A ‘+’ or ‘−’ above a bar indicates that the number of ChIP-seq reads for that bin and modification is significantly higher or lower, respectively, than the control for that bin (P < 0.001). A ‘+’ or ‘−’ within the bar indicates that a bin is significantly enriched or depleted, respectively, for the histone modification compared to the next lowest activity bin (P < 0.001). Error bars shown are the SEM.