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. 2011 Oct 19;40(4):1621–1635. doi: 10.1093/nar/gkr844

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Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — RECQL5 depletion is associated with late S-phase cycling defects. Representative flow cytometry images of (A and B) HeLa and (C and D) HCT116 scrambled and RECQL5 knockdown cells analyzed for the ability to incorporate bromodeoxyuridine (BrdU) and plotted against DNA content in (A and C) a 30 min BrdU pulse and (B and D) 24 h pulse. For panels A and C, the fraction of BrdU positive cells are denoted in the upper left. The late S-G2 of the BrdU positive cells subpopulation, boxed area, is also quantified in the upper right. For panels B and D, the first generation slow late S-G2 population is boxed and quantified.