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IL-4 and histamine repress the S100A7 secretion by epithelial cells. The nasopharyngeal epithelial cell line FaDu was cultured in the absence or presence of IL-4 (10 ng/ml) or histamine (10 μM) for 24 h followed by measurements of S100A7 in the culture supernatants by use of ELISA (n = 6). Data are presented as mean ± SEM. *, p < 0.05 (paired t-test).
