Results normalized by serum-free media control. Data represent mean ± SEM. After 24 hours or 48 hours, SK-N-BE(2)C cells treated with 0.5, 1, 2.5 and 5 nM did not show any significant difference at (A) viability, (B) proliferation, (C) apoptosis or (D) cytotoxicity levels (Student’s t test, p>0.05). Representative data for one concentration of rhVEGF165b (1nM) and one time point is shown.