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Matrix metalloproteinase (MMP) activity in CVC exposed to THP-1 cells or oxidized LDL (oxLDL). CVC grown in 6-well plates were cocultured with THP-1 cells or treated with 50 μg/ml of oxLDL for 3 days. A: MMP activity was assayed in the supernatant as described in materials and methods (#P < 0.01, *P < 0.05, n = 3). B: media supernatants were used to run casein zymogram. OxLDL and THP-1 increased casein-degrading activity in zymogram.
