Table 3.
Quantitative measurement of transcript levels in rat hippocampus
| Relative mRNA Levels Normalized to P7 IS |
|||||||
|---|---|---|---|---|---|---|---|
| P7 |
P15 |
P30 |
|||||
| Gene | IS | ID | IS | ID | IDT | IS | IDT |
| Hif1a | 1.00 ± 0.12b (5) | 1.02 ± 0.13 (5) | 0.60 ± 0.08a (11) | 0.84 ± 0.05** (7) | 0.56 ± 0.16 (10) | 0.73 ± 0.19a (6) | 0.78 ± 0.13 (6) |
| c-fos | 1.00 ± 0.10a (5) | 2.03 ± 0.09** (4) | 5.40 ± 1.43b (7) | 9.77 ± 1.23*** (4) | 4.63 ± 1.05 (7) | 6.16 ± 1.25b (7) | 9.58 ± 1.39** (6) |
| Dlgh4 (PSD95) | 1.00 ± 0.16a (6) | 0.47 ± 0.09*** (6) | 2.85 ± 0.47b (11) | 1.68 ± 0.25*** (8) | 2.59 ± 0.28 (11) | 4.06 ± 0.78c (5) | 4.23 ± 0.66 (7) |
| Mbp | 1.00 ± 0.20a (3) | 0.91 ± 0.06 (6) | 1564 ± 117c (5) | 784 ± 61** (6) | 986 ± 35** (5) | 742 ± 22b (5) | 615 ± 88* (6) |
Values are means ± SD; no. of rats in parentheses.
P, postnatal day; ID, iron deficient. Letters indicate significant intragroup difference with a < b < c by ANOVA. Intergroup difference as follows: *P < 0.05, **P < 0.01, and ***P < 0.001 by unpaired t-test.