. Author manuscript; available in PMC: 2012 Feb 27.

Published in final edited form as: JAMA. 2011 Jun 1;305(21):2184–2192. doi: 10.1001/jama.2011.715

Table 2.

Hazard ratios for the linear effect of femoral neck BMD T-score or FRAX score on hip and non-spine fracture among older adults with and without diabetes in Health ABC, SOF, and MrOS

		Without diabetes			With diabetes

Gender	Fracture site	No. with any fracture	HR^a,^b (95% CI)	C-index	No. with any fracture	HR^a,^b (95%CI)	C-index
Femoral Neck BMD T-score
Women	Hip	1117	2.23 (2.06, 2.41)	0.74	84	1.88 (1.43, 2.48)	0.72
	Non-Spine	3231	1.53 (1.47, 1.60)	0.62	262	1.52 (1.31, 1.75)	0.64
Men	Hip	158	3.53 (2.84, 4.38)	0.83	32	5.71 (3.42, 9.53)	0.85
	Non-Spine	690	1.62 (1.47, 1.77)	0.64	133	2.17 (1.75, 2.69)	0.66

FRAX score
Women	Hip	825	1.06 (1.05, 1.06)	0.74	51	1.05 (1.03, 1.07)	0.70
	Non-Spine	2383	1.04 (1.03, 1.04)	0.62	161	1.04 (1.02, 1.05)	0.64
Men	Hip	85	1.10 (1.08, 1.13)	0.80	16	1.16 (1.07, 1.27)	0.83
	Non-Spine	418	1.07 (1.06, 1.08)	0.65	73	1.09 (1.04, 1.14)	0.63

Abbreviation: HR = hazard ratio, CI = confidence interval.

Femoral neck BMD T-score models adjusted for age. HR per 1 unit decrease in T-score. FRAX score models are not adjusted for other variables. HR per 1 unit increase in FRAX score.

Diabetes status did not modify any of the associations (p for interaction>0.10) between FN T-score or FRAX score and fracture risk