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The effect of UCP2 deficiency on steatotic hepatocyte viability following hypoxia/reoxygenation. WT and UCP2 KO hepatocytes were incubated in control or intralipid-supplemented medium for 24 h (baseline) and subjected to 4 h of hypoxia, and survival was measured by Trypan exclusion at baseline and at 24 h following reoxygenation, as represented by box plot. n = 5/group; a,b,cmeans with different superscripts are significantly different; P < 0.05.
