Table 4.
Ten functional motif candidates
| Group:Motif ID | TF | Motif (ORI ≥ 61, Underline; MARE) | |
|---|---|---|---|
| E:12-7 | MYOD, GATA-1 | CAGCCAGCAGCA | |
| G:14-4 | CdxA | AGCTTTGAAGACAG | |
| F:16-2 | GATA-2, AP2 | CGGTCTCTGGGCTCAG | (Partially same strand of 14-2) |
| A:10 | AP4/AML(10ATCT..) | ATCTGCTGAC | Only group ”A” is extracted at Step1. |
| F:14-2 | AP2/ZID | CGGGCTCTGGGCTC | |
| F:,B:12-2 | AP2, AML-1a | AGCCCAGAGCCC | (Complementary strand of 14-2, 16-2) |
| D:10-10 | Nkx-2.5 | GTGCTGAGTG | |
| E:10-3 | GATA-1 | CCTGCTCCTG | (Complementary strand of 12-7) |
| B:16-4 | AML-1a | ACAGAGGCCCAGAGGG | (Partially same strand of 12-2) |
| C:10-9 | MZF1 | GCTGGGGCAG |
The top 10 functional motif candidates were optimized by ORI and are shown with their transcription factors and the IDs in the order of their score ranking. The IDs show both the number of nucleotides and the ranking order of extracted motifs, for example, the ID of the seventh extracted motif using N = 12 is ”12-7”. The motifs were grouped by sequence similarity with the same transcription factor. Two motifs, groups A and D, were identified as the MafB motif.