Table 6.
Label | Freq(Original) | Mean-Freq (Random) | S-Dev(Random) | Z-score | P-value |
---|---|---|---|---|---|
C~ | 4.66% | 4.07e-006% | 9.14e-007 | 51013 | < 10-3 |
C^ | 8.91% | < 10-2 | 4.29e-005 | 2075.1 | < 10-3 |
CN | 32.89% | 0.021% | < 10-6 | 225.64 | < 10-3 |
Cr | 0.55% | 1.14% | < 10-6 | -9.95 | > 10-2 |
CF | 19.58% | 41.82% | < 10-6 | -66.188 | > 10-2 |
CR | 33.40% | 57.06% | < 10-6 | -84.16 | > 10-2 |
Each type of 4-node subgraph shows its significance based on its structural uniqueness. The label is generated by Nauty program [24] and the corresponding shape is shown in Figure 1. In this network, the first three types are detected as network motifs.