Figure 5.

A protein interaction sub-network of FL_vs_L expanded differentially expressed proteins. Nodes colored in red or green are FL_vs_L differentially expressed proteins (seeds) and nodes in light purple are non-seed expanded proteins recruited through human protein interactions. Edges represent protein interactions recorded in the HAPPI database. Only HAPPI database protein interactions with quality ratings at or above 3 are used. Proteins that are significantly differentially expressed in FL_vs_CTRL or L_vs_CTRL conditions are also shown using the same color legend for FL_vs_L seed proteins, with the rectangle split into two half panels: the upper panel shows the gradient red (FC_CTRL_L >0) or green (FC_CTRL_L <0) colors for the FC_CTRL_L value, while the lower panel shows the gradient red or green color using the same color profile for the FC_CTRL_FL value. Standalone networks with only one pair of interactions are not shown.