Table 2.

Rank and nominal p-value from the association test between Q1 and the genes in the VEGF pathway included in the simulating model for Q1

	ARNT	ELAVL4	FLT1	FLT4	HIF1A	HIF3A	KDR	VEGFA	VEGFC
Rank	112	1,007	1	1,013	698	544	34	985	214
p-value	0.009	0.1359	2.4 × 10−13	0.1441	0.0885	0.0616	0.0017	0.1380	0.0186

The smallest p-value from either single SNP association of common variants or aggregate of rare variants within a gene was chosen to represent the gene. All models were adjusted for age, sex, smoking, and principal components.