Table 3.

P-values corresponding to the true causal genes using Q1 as phenotype

Chromosome	Gene	1% cutoff		3% cutoff
		Nuclear families	Pedigrees	Nuclear families	Pedigrees
1	ARNT	0.441	0.301	0.450	0.406
1	ELAVL4	0.447	0.347	0.952	0.948
4	KDRa	0.03	0.09	0.229	0.092
4	VEGFCa	0.009	0.317	0.009	0.317
5	FLT4	0.314	0.299	0.319	0.304
6	VEGFAa	0.0002	0.122	0.002	0.156
13	FLT1a	0.076	0.128	0.0003	0.024
14	HIF1A	NA	NA	0.317	0.317
19	HIF3A	0.508	0.466	0.638	0.609

^a Gene that has polymorphic causal SNPs. The other five causal genes (not marked by superscript a) cannot be identified in our method because there were no causal SNPs corresponding to those genes in the sample.