Table 1.
Population | Slope | Mean Tajima’s D | |||
---|---|---|---|---|---|
Estimate | Standard Error | p-value | Nonsynonymous SNPs | Synonymous SNPs | |
Tuscan | 0.576 | 0.005 | 3.30 × 10−15 a | −0.097 | 0.161 |
CEPH | 0.626 | 0.004 | 5.90 × 10−3 a | −0.151 | 0.140 |
Japanese | 0.644 | 0.005 | 6.60 × 10−8 a | −0.197 | 0.090 |
Han Chinese | 0.677 | 0.004 | 9.33 × 10−1 | −0.296 | −0.032 |
Denver Chinese | 0.677 | 0.004 | 1.30 × 10−3 a | −0.265 | −0.028 |
Yoruba | 0.694 | 0.003 | 8.80 × 10−2 | −0.461 | −0.213 |
Luhya | 0.701 | 0.003 | <2.2 × 10−16 a | −0.444 | −0.215 |
All | 0.902 | 0.002 |
Rare variant to total variant slope estimates and standard errors are given for each population and for all the populations pooled. The populations are ranked according to slope. Equality of slopes for contiguous populations (i.e., Tuscan vs. CEPH, CEPH vs. Japanese, etc.) is tested, and the p-value for each comparison is given. Finally, the mean values of Tajima’s D for each population calculated on the basis of nonsynonymous and synonymous SNPs are given.
a Significant difference between the population and the one immediately below.