Table 2.

Statistics aggregated across populations

Gene	Mean Tajima’s D	Variance of Tajima’s D	Total number of variants	Proportion of rare variants	Proportion of rare variants that are nonsynonymous
Nonsynonymous
AHNAK	−2.08	0.06	65.86	0.86	0.69
RELN	−1.97	0.02	33.43	0.74	0.59
POLE	−1.95	0.04	24.29	0.72	0.69
PIK3C2B	−1.83	0.19	21.29	0.62	0.56
PKD1	−1.49	0.39	22.86	0.71	0.61
RANBP2	NA	NA	24.57	0.82	NA
INVS	−1.72	0.22	9.43	0.82	0.75
NPC1L1	−1.70	0.10	13.71	0.83	0.58
BAIAP3	−1.73	0.05	13.29	0.81	0.63
RGPD4	−1.16	0.83	18.86	0.83	0.62
CEP250	−1.59	0.06	17.14	0.85	0.65
ATM	−1.38	0.19	5.29	0.95	0.77
GAB2	NA	NA	9.14	0.54	NA
DNMBP	−1.82	0.04	19.43	0.69	0.66
OR8H1	−1.24	0.29	6.86	0.63	0.93
CCDC63	−1.64	0.04	8.00	0.90	0.77
Average	−1.66	0.18	19.59	0.77	0.68
Synonymous
TACC2	−1.20	0.36	36.71	0.67	0.63
FRMPD2	−1.21	0.48	14.14	0.78	0.47
VPS26A	−1.33	0.36	0.57	NA	NA
MDN1	−1.20	0.95	54.29	0.71	0.64
PTPRS	−1.21	0.36	18.86	0.78	0.37
RGPD4	−1.62	0.13	18.86	0.83	0.62
C20ORF26	−0.89	1.48	21.71	0.73	0.71
H2AFY2	NA	NA	3.29	NA	NA
Average	−1.24	0.59	21.05	0.75	0.57

Tajima’s D, its variance, total number of polymorphisms, and the proportions of rare and nonsynonymous variants are given for each of the genes that reflect the most negative values of Tajima’s D (less than −2 for the analysis based on nonsynonymous SNPs and less than −1.8 for the analysis based on synonymous SNPs). NA (not applicable) corresponds to instances in which the value is not defined for at least one of the populations.