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Modeling the aggregate effects of common and rare variants in multiple genes (with knowledge of the answers) using latent variable structural equation modeling. Model of the associations between 9 genes (19 SNPs) simulated to affect Q1 (Q1 R2 = 0.42, CFI = 0.90, RMSEA = 0.04, SRMR = 0.03). * p < 0.10; ** p ≤ 0.05; *** p ≤ 0.01. Residuals and paths from population structure not shown for clarity.
