Table 1.

IBD filtering in phenotype file 1

Individuals	Genes shared	Total SNPs	Rare SNPs (MAF < 0.1)	Synonymous	Non-synonymous
+2	3,205	24,488	21,605	12,611	8,994
+3	3,193	24,353	21,482	12,528	8,954
+4	3,193	24,353	21,482	12,528	8,954
+5	3,020	23,531	20,730	12,104	8,626
+6	3,018	23,529	20,730	12,104	8,626
+7	2,985	23,336	20,553	11,995	8,558
+8	2,940	23,149	20,383	11,872	8,511
+9	2,924	23,056	20,308	11,830	8,478
+10	2,861	22,852	20,132	11,730	8,402
+11	2,844	22,741	20,035	11,667	8,368
+12	2,635	21,353	18,844	11,026	7,818
+13	2,564	20,914	18,451	10,815	7,636
+14	2,352	19,805	17,550	10,315	7,235
+15	2,221	18,654	16,554	9,731	6,823
+16	2,004	16,837	15,005	8,807	6,198
+17	1,780	15,433	13,748	8,085	5,663
+18	1,665	4,358	12,821	7,551	5,270
+19	1,532	13,125	11,709	6,868	4,841
+20	1,386	12,106	10,786	6,336	4,450
+21	1,236	10,857	9,676	5,681	3,995
+22	1,062	9,332	8,327	4,871	3,456
+23	906	8,133	7,280	4,251	3,029
+24	709	6,470	5,811	3,393	2,418
+25	622	5,520	4,959	2,858	2,101
+26	531	4,705	4,229	2,441	1,788
+27	450	4,352	3,911	2,258	1,653
+28	284	2,857	2,580	1,490	1,090
+29	195	2,090	1,903	1,100	803
+30	120	1,666	1,528	893	635
+31	51	867	789	452	337
+32	24	460	424	249	175
+33	1	16	16	12	4
+34	1	16	16	12	4
+35	0	0	0	0	0

Highlighted bold rows indicate the “most cases” and “max cases” respectively.