Table 1.
Causal gene with tested p-value
| Gene | p-value (Madsen and Browning method) | p-value (our method) |
|---|---|---|
| AKT3 | 0.173 | 1.0 |
| BCL2L11 | 0.0555 | 1.0 |
| ELAVL4 | 0.90 | 0.0283 |
| HSP90AA1 | 0.737 | 8.63 × 10−6 |
| NRAS | 0.459 | 1.0 |
| PIK3C2B | 1.48 × 10−5 | 8.67 × 10−10 |
| PIK3C3 | 0.796 | 1.0 |
| PIK3R3 | 0.732 | 0.236 |
| PRKCA | 0.564 | 1.0 |
| PRKCB1 | 0.684 | 0.236 |
| PTK2 | 0.868 | 1.0 |
| PTK2B | 0.433 | 1.0 |
| RRAS | 0.480 | 1.0 |
| SHC1 | 0.925 | 1.0 |
| SOS2 | 0.465 | 1.0 |
The causal genes of latent liability disease and their p-values found using Madsen and Browning’s method and our proposed method.