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. 2011 Nov 29;5(Suppl 9):S84. doi: 10.1186/1753-6561-5-S9-S84

Figure 2.

Figure 2

Observed LR statistics and theoretical mixture distribution. The density of observed LR statistics from LOD scores using SNPs in noncausal genes is plotted. For the first model without a SNP covariate, the theoretical distribution is a 50:50 mixture of a chi-square distribution with 1 df and a chi-square distribution with 2 df because we have one covariate. For the second model with a SNP covariate, the theoretical distribution is a 50:50 mixture of a chi-square distribution with 2 df and a chi-square distribution with 3 df because we have two covariates. The blue curve is for the observed LR statistics; the black curve is for the theoretical values.