Figure 5. Serotonin release.
Agonist-induced serotonin release was measured by high-sensitivity ELISA in a subset of 13 CAD patients treated with ASA and clopidogrel, among whom 9 were identified as clopidogrel responders (A) and 4 as low-responders (B). The following agonist/antagonist concentrations were used: 32 µM TRAP, 6.5 µM ADP, 10 µM ketanserin. * p<0.05 in ANOVA followed by Bonferroni's multiple comparison test.
