Table 1. Baseline clinical characteristics of CAD patients treated with ASA only and CAD patients treated with ASA and clopidogrel.
| Variable/parameter | ASA only(n = 9) | Clopidogrel low-responders(n = 12) | Clopidogrel responders(n = 30) | P (ASA only vs. ASA+clopidogrel) | P (clopidogrel low-responders vs. responders) |
| Age (years) Mean ± SD | 73±9 | 73±14 | 67±12 | 0.274 | 0.144 |
| Male gender | 7 (78) | 9 (75) | 18 (60) | 0.699 | 0.485 |
| Smokers | 4 (44) | 3 (25) | 15 (50) | 1.0 | 0.180 |
| Hypertension | 5 (56) | 7 (58) | 23 (77) | 0.436 | 0.274 |
| Dyslipidemia | 3 (33) | 6 (50) | 16 (53) | 0.465 | 1.0 |
| Diabetes mellitus | 3 (33) | 1 (8) | 4 (13) | 0.137 | 1.0 |
| Acute coronary syndrome | 0 | 6 (50) | 18 (60) | 0.732 | |
| Drug-eluting stent | 0 | 9 (75) | 20 (67) | 0.722 | |
| Bare-metal stent | 0 | 4 (33) | 10 (33) | 1.0 |
Healthy control subjects (n = 10) were 34±4 years old, 5 were male, 1 smoked and none suffered from the mentioned diseases. P values for the comparison of CAD patients with ASA only vs. all CAD patients with ASA+clopidogrel and for the comparison of clopidogrel low-responders vs. responders. Number of patients (%), unless otherwise indicated.