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. 2012 Feb 27;7(2):e29527. doi: 10.1371/journal.pone.0029527

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Conservation of mammalian NAGS DNA by phastCons (green) and phyloP (blue) algorithms is shown with the highly-conserved regions indicated in red boxes (A). Pair-wise blast analysis of mammalian non-coding regions of NAGS identified highly conserved sequences upstream of the translational start site termed the promoter (purple) and enhancer (cyan) (B).