Table 3. Proteome of the Growth Cone versus Transcriptome of the Growing Axon.
PROTEIN ISOFORMS (Rab; Kif) | SUBUNITS OF A LARGE PROTEIN COMPLEX | ||||
Rab | Proteome # spectra* | Transcriptome [30] | Psm** | Proteome # spectra* | Transcriptome [30] |
1a | 44 | ○ | Psma1 | 57 | X |
1b | 62 | X | Psma2 | 57 | ○ |
2a | 101 | X | Psma3(I) | 24 | X |
2b | 17 | ○ | Psma4 | 67 | ○ |
3a | 56 | ○ | Psma5 | 57 | ○ |
3b | 5 | ○ | Psma6 | 72 | X |
3c | 58 | ○ | Psma7 | 53 | ○ |
4a | 9 | ○ | Psmb1 | 70 | ○ |
4b | 11 | ○ | Psmb2 | 38 | ○ |
5a | 52 | ○ | Psmb3 | 47 | X |
5b | 41 | ○ | Psmb4 | 33 | X |
5c | 113 | ○ | Psmb5 | 73 | ○ |
6a | 63 | ○ | Psmb6 | 25 | X |
6b | 30 | X | Psmb7 | 50 | X |
7a | 92 | ○ | Psmb8 | 0 | X |
8a | 5 | ○ | Psmc1 | 84 | ○ |
9a | 5 | ○ | Psmc2 | 55 | X |
9b | 8 | ○ | Psmc3 | 119 | ○ |
10 | 83 | ○ | Psmc4 | 103 | X |
11b | 163 | ○ | Psmc5 | 105 | ○ |
14 | 132 | X | Psmc6 | 82 | X |
21 | 27 | ○ | Psmd1 | 399 | ○ |
23 | 14 | ○ | Psmd2 | 284 | ○ |
31 | 20 | ○ | Psmd3 | 122 | X |
33a | 11 | ○ | Psmd4 | 102 | ○ |
35 | 30 | ○ | Psmd5 | 47 | ○ |
Entries | 26 | 4 | Psmd6 | 94 | X |
Kif | Proteome # spectra * | Transcriptome [30] | Psmd7 | 108 | ○ |
1a | 76 | X | Psmd10 | 6 | ○ |
1b | 9 | ○ | Psmd11 | 118 | X |
2 | 28 | ○ | Psmd12 | 139 | X |
3a | 20 | ○ | Psmd13 | 150 | ○ |
3b | 7 | ○ | Psmd14 | 139 | ○ |
5a | 6 | ○ | Pmse1 | 21 | ○ |
5b | 80 | X | Psme2 | 148 | ○ |
5c | 222 | X | Psme3 | 42 | ○ |
21a | 32 | ○ | Psme4 | 28 | X |
21b | 66 | ○ | Psmf1 | 3 | ○ |
22 | 0 | X | - | - | - |
c2 | 0 | X | Entries | 37 | 16 |
Entries | 10 | 5 | **) Italicized symbols indicate structural proteasome subunits |
*) Net spectral numbers.
x) mRNA detected in mouse growth cones.