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. 2012 Feb 27;7(2):e31948. doi: 10.1371/journal.pone.0031948

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The two purified human topical thrombin products were heat-treated as described in Fig. 3. Control samples were heated in for 17 h at 60°C in PBS (in the absence of 60% sucrose). Binding of either the antibody or each of the six aptamers was monitored to (A) Recothrom or (B) Evithrom at time 0 and 17 h. The percent of the binding at time 0 (mean ± SD, n = 3) is represented. The aptamers used are shown on the figure.