Table 2.

Data source, sample size (n), and number of activation foci for all studies included in the meta-analysis.

Study	Stimulus Type	Stimulus Duration (s)	Data Source	n	Foci
Non-deprived Smokers
McBride et al. (2006)	Videos	120	Table 3	19	5
David et al. (2007)^a	Pictures	5	Table 1	8	2
Brody et al. (2007)	Videos	45	Table 1	42	17
McClernon et al. (2008)	Pictures	4	Table S6	30	18
Janes et al. (2009)	Pictures	4	Table 1	13	25
Rubinstein et al. (2011)	Pictures	18^b	Table 2	12	4
Franklin et al. (2011a)	Videos	600	Table 3	26	1
Hartwell et al. (2011)	Pictures	24^c	Table 1	31	12
Total			—	181	84
Deprived Smokers
David et al. (2005)	Pictures	5	Table 1	9	3
Lee et al. (2005)	Pictures	30	Table 2	8	11
David et al. (2007)^a	Pictures	5	Table 1	8	2
McClernon et al. (2009)	Pictures	60^d	Table 1	18	19
Total			—	43	35
Totals for pooled analysis			—	224	119

This study used a within-subjects design, in which the same participants were scanned when non-deprived and when deprived of cigarettes for 12 h. For purposes of the pooled meta-analysis, these two conditions were modeled as independent studies. Thus, the effective sample size for the pooled analysis was 224, even though there were only 216 individual smokers enrolled across all studies.

This study used a blocked design, in which the 18 s stimulation period consisted of consecutive presentation of 3 pictures from the same category for 6 s each. In the study, the data were modeled as a single, 18 s stimulus.

This study used a blocked design, in which the 24 s stimulation period consisted of consecutive presentation of 5 pictures from the same category for 4.8 s each. In the study, the data were modeled as a single, 24 s stimulus.

This study used a blocked design, in which the 60 s stimulation period consisted of consecutive presentation of 10 pictures from the same category for 6 s each. In the study, the data were modeled as a single, 60 s stimulus.