Table 1.
Clinical and quantitative imaging data of the patients.
| Patient No./gender | Age (years) | Epilepsy duration (years) | Seizure frequency [score] | IQ | Location of vascular malformation | Occipital CBF AI/FDG AI | Parietal CBF AI/FDG AI | Temporal CBF AI/FDG AI | Frontal CBF AI/FDG AI |
|---|---|---|---|---|---|---|---|---|---|
| 1/M | 7.0 | 6.5 | >10/day [5] | 47 | lFPO | -0.80/-0.41 | -1.04/-0.35 | -0.13/-0.27 | -0.62/-0.23 |
| 2/F | 2.0 | 1.9 | 1/year [2] | 55 | lFTPO | -0.96/-0.83 | -0.37/-0.88 | -0.18/-0.73 | -0.12/-0.69 |
| 3/F | 10.0 | 9.8 | monthly [3] | 55 | lFTPO | -0.72/-0.43 | -0.57/-0.57 | -1.34/-0.51 | -0.40/-0.12 |
| 4/F | 5.0 | 4.5 | <1/year [1] | 117 | lTO | -0.67/-0.29 | -0.18/-0.14 | -0.48/-0.34 | 0.36/-0.05 |
| 5/M | 5.0 | 0.5 | monthly [3] | 99 | rPO | -0.12/-0.71 | -0.21/-0.51 | 0.09/-0.12 | 0.00/0.04 |
| 6/M | 1.8 | 1.0 | 10/mo [4] | 105 | lTPO | -0.70/-0.80 | -0.39/-0.53 | -0.40/-0.66 | 0.02/-0.09 |
| 7/F | 0.9 | 0.6 | few/month [3] | not available | rFTPO | -0.12/-0.29 | -0.13/-0.17 | -0.22/-0.21 | -0.15/0.10 |
| 8/M | 4.0 | 0.5 | weekly [4] | 110 | lPO | -0.21/-0.97 | -0.12/-0.08 | 0.04/-0.18 | 0.02/-0.03 |
| 9/M | 9.0 | 8.4 | 1/year [2] | 93 | lP | -0.02/-0.01 | -0.22/-0.39 | -0.17/-0.10 | 0.07/-0.04 |
| 10/F | 1.6 | 1.0 | few/year [2] | 71 | rFTPO | 0.55/-0.44 | 0.26/-0.34 | 0.21/-0.22 | 0.51/0.06 |
| 11/M | 1.8 | 0.2 | few/year [2] | 92 | rTPO | 0.24/-0.04 | 0.38/-0.11 | 0.13/-0.00 | 0.03/0.02 |
| 12/F | 2.0 | -- | 0 [1] | 105 | lTPO | 0.24/-0.01 | 0.23/0.11 | 0.30/-0.06 | -0.02/-0.04 |
| 13/F | 4.0 | 2.0 | <1/year [1] | 102 | lP | -0.00/-0.03 | 0.30/-0.04 | 0.01/-0.07 | -0.09/-0.03 |
| 14/F | 4.0 | 3.9 | <1/year [1] | 91 | lFP | -0.04/-0.00 | 0.29/-0.12 | -0.00/-0.05 | 0.24/-0.29 |
| 15/F | 8.0 | 3.5 | 1/year [2] | 101 | rO | -0.05/-0.14 | -0.01/-0.10 | 0.02/-0.13 | -0.04/-0.03 |
Note: M: male, F: female, y: years, seizure frequency score definition: 1 if <1 seizure per year; 2 if 1-11 seizures per year; 3 if 1-3 seizure(s) per month; 4 if 1-6 seizure(s) per week; 5 if ≥1 seizure(s) per day; IQ: a measure of global intellectual functioning determined by age-appropriate tests; l: left, r: right, F: frontal, T: temporal, P: parietal, O: occipital, CBF: cerebral blood flow, FDG: 2-deoxy-2[18F]fluoro-D-glucose, AI: asymmetry index; FDG AI refers to glucose SUV asymmetry of the corresponding lobe. AI = 2 × (I - C) / (I + C), where I refers to values measured in the affected (ipsilateral) hemisphere and C refers to those of the contralateral side. Red values indicate abnormal decreases and green values indicate abnormal increases of CBF and FDG uptake on the affected side. Values with yellow background indicate abnormal CBF or FDG uptake values in a lobe with no vascular malformation.