Table 2.
Pearson correlation analysis
| AhR | CYP1A1 | ApoA1 | PON1 | PON1LPX | PON1LPH | PON1SPX | PON1SPH | |
|---|---|---|---|---|---|---|---|---|
| Dose-response-- | ||||||||
|
| ||||||||
| AhR | -- | 0.63 | 0.62 | 0.43 | 0.63 | 0.49 | 0.85 a | 0.81 a |
| CYP1A1 | -- | -- | 0.35 | 0.81 a | 0.88 a | 0.89 a | 0.68 a | 0.85 a |
| ApoA1 | -- | -- | -- | −0.07 | 0.13 | 0.01 | 0.71 | 0.58 |
| PON1 | -- | -- | -- | -- | 0.90 a | 0.87 a | 0.51 a | 0.69 a |
| PON1LPX | -- | -- | -- | -- | -- | 0.96 a | 0.62 | 0.72 a |
| PON1LPH | -- | -- | -- | -- | -- | -- | 0.48 | 0.64 |
| PON1SPX | -- | -- | -- | -- | -- | -- | -- | 0.94 a |
| PON1SPH | -- | -- | -- | -- | -- | -- | -- | -- |
|
| ||||||||
| Time-course | ||||||||
|
| ||||||||
| AhR | -- | 0.91 a | 0.27 | 0.86 a | 0.78 a | 0.75 a | 0.65 a | 0.65 a |
| CYP1A1 | -- | -- | 0.34 | 0.91 a | 0.80 a | 0.74 a | 0.82 a | 0.81 a |
| ApoA1 | -- | -- | -- | 0.34 | −0.04 | −0.11 | 0.17 | 0.50 |
| PON1 | -- | -- | -- | -- | 0.63 a | 0.59 a | 0.77 a | 0.72 a |
| PON1LPX | -- | -- | -- | -- | -- | 0.99 a | 0.76 a | 0.67 a |
| PON1LPH | -- | -- | -- | -- | -- | -- | 0.72 a | 0.62 a |
| PON1SPX | -- | -- | -- | -- | -- | -- | -- | 0.89 a |
| PON1SPH | -- | -- | -- | -- | -- | -- | -- | -- |
Value denotes the Pearson correlation coefficient r,
a
indicates a statistically significant correlation (p<0.05)
Abbreviation: PON1LPX (liver PON1 activity towards paraoxon), PON1LPH (liver PON1 activity towards phenylacetate), PON1SPX (serum PON1 activity towards paraoxon), PON1SPH (serum PON1 activity towards phenylacetate)