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. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: Cancer Gene Ther. 2011 Nov 25;19(3):192–201. doi: 10.1038/cgt.2011.77

Figure 6. Inhibition of MC38 and B16 tumor growth in nude mice treated with the two viruses.

Figure 6

Subcutaneous MC38 or B16 cancers were established in nude mice. When cancers reached about 5 × 5 mm (~ day 14), mice were treated with PBS saline, vJS6 or vFasL at 1.0 × 107 pfu/mouse (n = 8 to 10). (a) The growth curves of FasR− B16 melanoma. Significant difference in B16 tumor volumes in groups of mice was observed [p = 0.003 by ANOVA; vJS6 versus vFasL: p < 0.05 by one tailed, two samples, equal variance T-test]. (b) The growth curves of FasR+ MC38 colon cancer. Significant difference in tumor volumes in groups of mice was observed [p = 0.011 by ANOVA; vJS6 versus vFasL: p < 0.05 by one tailed, two samples, equal variance T-test].