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. Author manuscript; available in PMC: 2013 Feb 15.
Published in final edited form as: Bioconjug Chem. 2012 Jan 26;23(2):293–299. doi: 10.1021/bc200390q

Figure 1.

Figure 1

General strategy for purifying proteins using oligovalent ligands. The ligands induce aggregation of monovalent proteins and reduce their solubility in aqueous solutions containing dissolved ammonium sulfate.