Table 1.

Estimated differences of coefficients of cross-correlation between significant and minimal fatigue stages (i.e. significant-minimal) and their standard errors based on linear regression models. The statistical tests were performed to evaluate whether FC is greater in significant than minimal fatigue stages for sub-region ROIs in the PM/SMA and PFC not shown in Fig. 7, 8 and 9.

ROI	Estimate	Std Err	ROI	Estimate	Std Err
Premotor Cortex Sub Regions (Mayka et al., 2006)
Left PMd	0.0568	0.0006	Right PMd	0.0326	0.0006
Left PMv	0.0388	0.0005	Right PMv	0.0543	0.0006
Left preSMA_L	0.0642	0.0009	Right preSMA	0.0493	0.001
Left SMA proper	0.0302	0.0011	Right SMA proper	0.035	0.001
Prefrontal Cortex Sub Regions (Tzourio-Mazoyer et al., 2002)
Left mPFC	0.0886	0.0005	Right mPFC	0.104	0.0005
Left DLPFC	0.0704	0.0004	Right DLPFC	0.0702	0.0003
Left VLPFC	0.1162	0.0006	Right VLPFC	0.0871	0.0006
Left omPFC	0.1334	0.0029	Right omPFC	0.1634	0.0027

All tests exhibited significant differences in FC between the two fatigue stages (P<0.001 for all ROIs). PMd=dorsal premotor, PMv=ventral premotor, preSMA=rostral SMA, SMA proper=caudal SMA, mPFC= medial PFC, DLPFC=dorsolateral PFC, VLPFC=vetrolateral PFC, and omPFC=orbito-medial PFC.