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Systolic blood pressure (SBP) and urinary protein/creatinine ratio (UPCR). (a) Angiotensin II (AngII)-salt treatment elevated the blood pressure in mice. The hypertension was suppressed by olmesartan or hydralazine, but not by eplerenone. (b) Protein excretion in the urine was increased by AngII-salt. The increase in proteinuria was suppressed by olmesartan, but not by eplerenone or hydralazine. *P < 0.05 vs. vehicle, #P < 0.05 vs. AngII.
