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. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: Nat Genet. 2012 Jan 29;44(3):251–253. doi: 10.1038/ng.1102

Figure 1. Recurrent somatic mutations in H3F3A and HIST1H3B.

Figure 1

Sanger sequencing chromatograms showing representative H3F3A or HIST1H3B mutations encoding p.K27M substitutions, or H3F3A mutation encoding p.G34R substitution in the indicated tumour compared to matched normal DNA. Arrow indicates mutation. SJHGG001 and SJHGG079 are DIPGs, SJHGG043 is a non-brainstem paediatric glioblastoma.