Skip to main content
. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: Nat Chem Biol. 2012 Jan 29;8(3):270–276. doi: 10.1038/nchembio.772

Figure 4. Temporal dynamics of Ntla-dependent mesoderm development.

Figure 4

a, Expression of flh at 10 hpf in wildtype embryos, conventional ntla morphants, and embryos injected with the ntla cMO and irradiated globally at either 4, 5, or 6 hpf. Micrographs depicting four phenotypic classes of flh expression and the phenotypic distributions associated with each experimental condition are shown. b, Expression of fgf8a at 10 hpf in wildtype embryos, conventional ntla morphants, and embryos treated in analogous manner. Micrographs depicting four phenotypic classes of fgf8a expression and the phenotypic distributions associated with each experimental condition are shown. c, A model for Ntla-dependent patterning of the axial mesoderm. Approximate times for patterning events within the trunk mesoderm, as suggested by ntla cMO phenotypes, are indicated in parentheses. Embryo orientations: dorsal view and anterior up. Scale bars: 100 μm.