Table 1.

Animal/liver weights and liver-body weight ratios at necropsy.

Group		n	Weight (g)	Liver (g)	Liver:BW ratio	Visible Lesions
MALE (24 Wks)	Control (C)	9	35.6±0.5	1.81±0.05	0.050±0.001	0
	EtOH (E)	9	35.1±0.7	2.14±0.09	0.056±0.002	0
	DEN (D)	9	36.9±2.4	2.10±0.17	0.057±0.002	0
	DEN+EtOH (D+E)	14	34.8±0.7	2.08±0.12	0.059±0.002	0
FEMALE (24 Wks)	Control (C)	10	25.7±0.4	1.30±0.03	0.051±0.001	0
	EtOH (E)	10	27.5±0.4	1.48±0.03	0.054±0.015	0
	DEN (D)	9	27.9±0.6	1.64±0.09*	0.059±0.003	0
	DEN+EtOH (D+E)	14	25.4±0.4	1.35±0.03	0.053±0.006	0
Group		n	Weight (g)	Liver (g)	Liver:BW ratio	Visible Lesions
MALE (48 Wks)	Control (C)	9	41.2±1.0	1.93±0.05	0.047±0.001	0
	EtOH (E)	9	42.1±0.8	2.19±0.06	0.054±0.001	0
	DEN (D)	8	36.3±2.3#	2.59±0.35#	0.070±0.007#	87.5% (7/8)
	DEN+EtOH (D+E)	14	34.7±0.7#	4.44±0.16*	0.129±0.006*	93.7% (13/14)
FEMALE (48 Wks)	Control (C)	10	27.9±0.6	1.37±0.05	0.049±0.001	0
	EtOH (E)	10	28.6±0.5	1.41±0.04	0.049±0.001	0
	DEN (D)	9	28.2±0.8	1.78±0.14*	0.063±0.005*	44.4% (4/9)
	DEN+EtOH (D+E)	14	25.7±1.1*	1.31±0.07	0.050±0.001	35.7% (5/14)

^*p<0.05 versus all other treatments groups within male or females assayed at matching time points (24 or 48 weeks).

^#p<0.05 versus C or E within male or female groups assayed at matching time points.