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. Author manuscript; available in PMC: 2013 Mar 1.
Published in final edited form as: J Immunol. 2012 Jan 27;188(5):2198–2206. doi: 10.4049/jimmunol.1102813

Figure 5. Evolution of proliferation and activation profiles of Gag-responsive IFNγ positive T cells.

Figure 5

(A) Representative dot plots of IFNγ, TNFα and CD38, Ki67 expression profiles in Gag-responsive CD4+ (left panel) and CD8+ (right panel) T cells at less than 120 days after Fiebig I/II staging (early) or more than 120 days after Fiebig I/II staging (chronic). The grey density plots represent total memory T cell population staining for CD38/Ki67 cells and the red dots correspond to IFNγ+ Gag-responsive T cells. Longitudinal assessments of the proportion of Ki67+IFNγ+CD4+ T cells (B) and Ki67+IFNγ+CD8+ T cells (C). Longitudinal assessments of the proportion of CD38+IFNγ+CD4+ T cells (D) and CD38+IFNγ+CD8+ T cells (E). Linear and non-linear regression analyses are depicted with black solid lines.