. Author manuscript; available in PMC: 2013 Apr 1.

Published in final edited form as: Biochem Pharmacol. 2012 Jan 20;83(7):932–940. doi: 10.1016/j.bcp.2012.01.015

Table 2.

Sciatic nerve and spinal cord glucose, sorbitol, and fructose concentration (nmol mg⁻¹ protein) in control and diabetic mice maintained with and without fidarestat treatment.

Groups Variables	Control	Control+Fidarestat	Diabetic	Diabetic+Fidarestat
Sciatic nerve
Glucose	16.30 ± 1.47	18.75 ± 1.31	63.53 ± 9.04^**	64.52 ± 6.84^**
Sorbitol	0.27 ± 0.03	0.23 ± 0.02	1.20 ± 0.13^**	0.22 ± 0.02^**,^##
Fructose	1.27 ± 0.50	0.23 ± 0.02	14.72 ± 0.72^**	1.00 ± 0.08^##
Spinal cord
Glucose	1.38 ± 0.27	1.07 ± 0.39	8.14 ± 1.76^**	7.15 ± 1.52^**
Sorbitol	0.84 ± 0.06	0.79 ± 0.08	1.49 ± 0.12^**	0.77 ± 0.08^##
Fructose	0.83 ± 0.22	0.85 ± 0.23	1.68 ± 0.25^*	0.99 ± 0.20^#

Data expressed as Mean ± SEM. n = 7–12 per group.

^*,**

p < 0.05 and p < 0.01 vs control mice,

^#,##

p < 0.05 and p < 0.01 vs diabetic mice.