Table 2. When PWR1 is also detected, high-copy FLO11 transcripts are present in cells more often than predicted by chance.
Pearson’s chi-square analyses to generate p-values were conducted under the null hypothesis that PWR1 and FLO11 transcription are independent. Total number of imaged cells is given by n.
| Genotype | n | % of cells in population with: | If PWR1 > 0, then also FLO11 > 5? | ||||
|---|---|---|---|---|---|---|---|
| FLO11 > 5 | PWR1 > 0 | Under Null, Expected: | Observed: | Fold-increase: | p-value: | ||
| WT | 10730 | 39.25% | 2.68% | 39.25% | 87.50% (252/288) | 2.23x | 8.71E-65 |
|
| |||||||
| cti6 | 13273 | 3.56% | 0.69% | 3.65% | 13.04% (12/92) | 3.57x | 8.57E-07 |
|
| |||||||
| cti6 pMET-ICR1 | 15751 | 12.67% | 0.89% | 12.67% | 60.71% (85/140) | 4.79x | 4.93E-66 |
|
| |||||||
| cti6 ΔpICR1 | 11187 | 14.38% | 1.68% | 14.38% | 67.55% (127/188) | 4.70x | 1.80E-97 |
|
| |||||||
| cti6 icr1::Term | 14407 | 7.05% | 1.58% | 7.05% | 67.40% (153/227) | 9.56x | 1.22E-280 |