Table 1.

Measurements achieved in ovariectomized animals (n=5) using traditional two-dimensional techniques are shown along with three-dimensional measures from the same specimens (mean ± SD). The paired difference between the two approaches is determined within each specimen and the average value across all specimens is shown.

	Two-Dimensional (2D measure)	Three-Dimensional (3D measure)	Paired Difference (2D–3D)/2D*100%
ES/BS (%)	5.01 ± 0.48%	4.79 ± 0.66%	−2.33 ± 8.31%
dLS/BS (%)	10.9 ± 1.79%	14.2 ± 2.15%	1.57 ± 0.19%
MAR (μm/d)	0.92 ± 0.07	0.94 ± 0.44	−3.00 ± 0.06%