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. Author manuscript; available in PMC: 2013 Feb 1.
Published in final edited form as: J Bone Miner Res. 2012 Feb;27(2):486–495. doi: 10.1002/jbmr.553

Table 2.

Static histomorphometric measures made using the three-dimensional approach are shown (mean ± SD, n=5 per group).

SHAM OVX
Bone Volume Fraction 31.5 ± 7.52% 19.7 ± 4.0% a
Bone Specific Surface (BS/TV, mm−1) 29.2 ± 2.20 22.8 ± 2.17 a
Trabecular Thickness (Tb.Th, μm) 81.3 ± 8.07 70.5 ± 3.26 a
Trabecular Separation (Tb.Sp, μm) 221 ± 41.1 310 ± 30.4 a
Structural Modeling Index (SMI) 0.96 ± 0.23 1.38 ± 0.33 a
Degree of Anisotropy (DA) 0.68 ± 0.07 0.68 ± 0.49
Percent Eroded Surface 2.54 ± 0.13% 4.79 ± 0.66% b
Number of Resorption Cavities (N.Cv) 105 ± 3.96 134 ± 13.6 b
Number of Resorption Cavities/BS (N.Cv/BS, mm−2) 2.38 ± 0.24 3.86 ± 0.35 b
Mean Cavity Resorption Depth (μm) 4.23 ± 1.85 3.99 ± 0.88
Maximum Cavity Resorption Depth (Cv.De, μm) 14.8 ± 2.56 14.0 ± 1.96
Average Cavity Surface Area (BS/Cv, μm2) 9,720 ± 1,060 11,200 ± 1,850
Average Cavity Volume (Cv.V, μm3) 36,500 ± 5,350 52,500 ± 13,900
Total Volume Occupied by Resorption Cavities (Tt.Cv.V/BV) 0.38 ± 0.06% 1.12 ± 0.18% c
a

p<0.05,

b

p<0.01,

c

p<0.001as compared to the sham operated group