Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
(a) Hepatic microsomal stability of compound 1. The half-life (t1/2) of the inhibitor was calculated from its decrease with time, using linear regression. (b) Serum concentration of compound 1 in mice injected (i.p.) with compound 1 at 3 mg/kg; blood serum was collected after 5, 20, 60, and 120 min.
