Fig. 2.

Histopathology of paraffin sections from the lumbar spinal cords of mice immunized with MOG35–55. H&E staining showing typical inflammatory cellular infiltrates of spinal cord white matter at the peak of EAE in (A) Wt mice (20 days post immunization, clinical score 3), (B) Wt mice following rGMF administration (19 days post immunization, clinical score 4), (C) GMF-KO mice (26 days post immunization, clinical score 1.5), and (D) GMF-KO mice following rGMF administration (22 days post immunization, clinical score 3). Images at 20X magnification