Figure 1.
Standardized Odds Ratios of Frailty Transitions, per 5 ng/mL Lower 25(OH)D
Standardized odds ratios and 95% confidence intervals per 5 ng/mL lower 25(OH)D. Arrowheads indicate confidence intervals that extend beyond the figure limits.
Standardized for age (years), sex, education (years), season of blood collection, smoking (pack-years), alcohol consumption (drinks/wk), body mass index (kg/m2), Mini-Mental State Examination, Center for Epidemiologic Studies – Depression Scale, comorbidities (congestive heart failure, peripheral arterial disease, hypertension, diabetes, osteoarthritis, renal disease, myocardial infarction, angina, chronic obstructive pulmonary disease), calcium intake (mg/day), and creatinine clearance (mL/min)
Model 1: Relationship between 25(OH)D and frailty status without including parathyroid hormone (PTH) in the model as a potential mediator
Model 2: Relationship between 25(OH)D and frailty status including parathyroid hormone in the model as a potential mediator; interpreted as the association between 25(OH)D and frailty status if PTH were set to low (<32.4 ng/L).